I am using my Mint desktop with a USB mouse.  Nothing unusual about the mouse.  It is a Logitech wired USB two-button, wheel mouse that I picked up from a local office supply store.  The pointer moves way too fast for my taste.  Even my daughter said it was way too fast.

The solution usually is to adjust the speed sliders in the Mouse section of System Settings.  I already set them to their slowest settings, so something needed to change under the hood.  This web page had the answer:

http://patrickmylund.com/blog/lowering-gaming-mouse-sensitivity-in-ubuntu-9-10/

In Mint I found that the first command to run in terminal is “xinput -list” which will give some information about your pointing device.  Mine says my mouse is “ImExPS/2 Logitech Explorer Mouse”.  Then this command is all it took to slow down the mouse:

xinput -set-prop “ImExPS/2 Logitech Explorer Mouse” “Device Accel Constant Deceleration” 3

With some experimentation I determined that the higher the number at the end of that command, the slower the mouse will move.  For me, “3” worked out nicely.